Modeling, Stability and Numerical Simulation of Doxorubicin Transport and Uptake in Tumors.


  • Daniela Cortes
  • Giuseppe Romanazzi



Difusion-Convection, Interstitium, Stability


This work analyzes the transport and effect of the chemotherapy drug doxorubicin in tumors. Specifically, we model the diffusion-convection process of doxorubicin delivered by bolus injection across the tumor and interstitium by a system of partial differential equations. We present a stability analysis of the system solution and implement a finite difference method to approximate it.


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Biografia do Autor

Daniela Cortes

IMECC, Campinas, SP

Giuseppe Romanazzi

IMECC, Campinas, SP


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