Modelo para a dinâmica do HIV com mutação
DOI:
https://doi.org/10.5540/03.2021.008.01.0446Keywords:
HIV, Modelagem Matemática, MutaçãoAbstract
Este trabalho apresenta um modelo de equações diferenciais e integro-diferenciais para a dinâmica da infecção pelo vírus da imunodeficiência adquirida (HIV). Tais modelos levam em conta os processos de mutação que o vírus sofre depois de adentrar o sistema imunológico. O objetivo é acompanhar a evolução da dinâmica do vírus no sistema imunológico, uma vez que células de defesa (CTL) são recrutadas para combater exclusivamente cada uma das mutações. Como essas células não estarão disponíveis para combater diferentes cepas, é muito importante entender e modelar a evolução das cepas a fim de prevenir o colapso do sistema imunológico.
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